Variant Effects Seminar Series - April 2024

Seminars are held on the 1st Tuesday each month from 9-10am Pacific (4-5pm UTC).

Ian Hoskins Pronouns: he/him

Cenik Lab, UT Austin

Integrated multiplexed assays of variant effect reveal cis-regulatory determinants of catechol-O-methyltransferase gene expression

Ian Hoskins was raised in Colorado and received his Bachelor’s of Science in Integrative Biology with a minor in Chemistry from The University of Colorado at Denver. He entered the biotechnology sector and worked at Enzymatics, Inc. and ArcherDX, Inc. between 2013 and 2018 developing genomic assays and software for clinical cancer research. Ian was admitted in The University of Texas at Austin Microbiology graduate program in 2018 and joined the lab of Dr. Can Cenik as his supervisor’s first graduate student.

Gabriella Estevam Pronouns: She/Her

Fraser Lab, UCSF

Exploring the landscape of MET kinase domain mutations and inhibitor resistance

Gabriella is a recent alum of the Fraser Lab at UCSF, where she studied the phenotypic and resistance landscape of the MET receptor tyrosine kinase. Her research focused on deciphering kinase domain regulatory motifs and resistance mechanisms to tyrosine kinase inhibitors. Additionally, she studied the relationship between the MET kinase domain and juxtamembrane.