News coverage of recent work:
Media contact: Dean R. Owen; dean1227@uw.edu; (+1) 253-906-8645
May 17, 2022 | by BBI Communications
Lead organizer of the 5th Annual Mutational Scanning Symposium, in-person and online, June 13 and 14 in Toronto
Read MoreMay 16, 2022 | by BBI Communications
It’s become a cliché: “They are wise beyond their years.” Unless you’re referring to Debora Ferede.
Read MoreMay 12, 2022 | by Michael McCarthy
The finding supports theory that genetic differences between individuals and species can affect the acquisition of mutations.
Read MoreApril 29, 2022 | by BBI Communications
A Q&A with BBI researchers reveals why the merger of two sequencing systems was crucial to landmark study
Read MoreApril 29, 2022 | by BBI Communications
BBI’s Dr. Danny Miller and the UW’s Nanopore Sequencing Core are providing both targeted and whole genome long read sequencing on the Oxford Nanopore platform to assist other researchers with their projects.
Read MoreApril 28, 2022 | by BBI Communications
With just six weeks away from the opening session, the fifth annual Mutational Scanning Symposium, to be held in-person and online June 13 and 14 in Toronto, now has most of its speakers confirmed.
Read MoreApril 28, 2022 | by BBI
BBI Member Alison Paquette, PhD, is an Assistant Professor in the Department of Pediatrics at the University of Washington School of Medicine and a member of the Seattle Children's Research Institute's Center for Developmental Biology and Regenerative Medicine.
Read MoreApril 12, 2022 | by BBI Communications
‘Killing is not the hard part for the immune system. The hard part is precisely killing the right thing.’
Read MoreApril 07, 2022 | by BBI Communications
'The evolution has been remarkably fast so far'
Read MoreApril 01, 2022 | by BBI Communications
‘Our view of how humans differ from each other is going to be transformed’
Read MoreApril 01, 2022 | by BBI Communications
Take one enthusiastic high school science teacher. Combine with summer internships at an international pharmaceutical company and a leading academic research center. The result is an inspired college undergraduate and promising young scientist. That was Amanda Riley seven years ago.
Read MoreMarch 31, 2022 | by Stephanie Perry, UW Medicine Communications Specialist
Alumnus Dr. Colin Pritchard’s genetic research career and his gift to help future researchers.
Read MoreMarch 30, 2022 | by BBI Communications
BBI is sponsoring a “Viruses and Vaccines Seminar Series.”
Read MoreMarch 29, 2022 | by BBI Communications
The Brotman Baty Institute is co-sponsoring the fifth annual Mutational Scanning Symposium to be held in-person and online June 13 and 14 in Toronto, followed by an online only poster session on June 16th. More information, including registration details, are available here.
Read MoreMarch 28, 2022 | by Sarah Cobey, Jesse Bloom and Tyler Starr, and Nathaniel Lash
NOTE: BBI’s Dr. Jesse Bloom and his lab colleague Dr. Tyler Starr are two of the four co-authors on this op-ed published March 28 in The New York Times. To observe the compelling accompanying graphics, please click here.
Read MoreMarch 28, 2022 | by BBI Communications
Initial results of the BBI-sponsored SeqFirst Project using whole genome sequencing have demonstrated that “clear opportunities exist to center equity for providing a precise genetic diagnosis that adds value to the care of critically ill newborns.”
Read MoreMarch 25, 2022 | by BBI Communications
BBI will be part of a major development approved recently by the UW Board of Regents – an 11-story building in the Portage Bay Crossing area on the west side the UW campus.
Read MoreMarch 17, 2022 | by UW Medicine
The nearly 100,000 whole genome sequences reflect contributions from diverse participants.
Read MoreMarch 14, 2022 | by UW Medicine | Newsroom
BBI scientists and others have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.
Read MoreFebruary 28, 2022 | by BBI Communications
‘Hope to potentially deliver more information and more confidence in assessing the potential – or even likelihood – of children relapsing’
Read MoreFebruary 28, 2022 | by BBI Communications
Today we are joined by BBI member Dr. Swati Shree, Assistant Professor in Maternal Fetal Medicine in the Department of Obstetrics and Gynecology at the University of Washington.
Read MoreFebruary 17, 2022 | by BBI Communications
The Brotman Baty Institute Advanced Technology Lab (BAT Lab) will soon be evaluating animal and plant specimens as part of a new UW initiative to help combat international wildlife trafficking.
Read MoreFebruary 14, 2022 | by BBI Communications
“Technological advances are making the routine sequencing of human genomes increasingly practical, including in clinical settings. However, our inability to interpret the clinical consequences of genetic variants discovered by sequencing remains a critical roadblock.”
Read MoreFebruary 07, 2022 | by BBI Communications
Dr. Helen Chu discusses Covid testing with Kim Malcolm
Read MoreFebruary 02, 2022 | by BBI Communications
Ashley Doyle, a client of BBI’s ConnectMyVariant with hereditary cancer, is making a ‘Herculean effort” to connect with relatives near and far, urging them to seek genetic testing.
Read MoreJanuary 28, 2022 | by BBI Communications
Moez Dawood: Pushing Himself Outside His Comfort Zone and Using BBI Technologies to Address Unanswered Questions in Human Genetics
Read MoreJanuary 24, 2022 | by BBI Communications
Storylines: Bloomberg Businessweek documentary examines Seattle Flu Study with BBI’s Drs. Lea Starita and Trevor Bedford
Read MoreJanuary 24, 2022 | by BBI Communications
‘It’s one thing to find a genetic variant. But how does that affect the brain architecture, structure, and function? We wanted to know more.’
Read MoreJanuary 19, 2022 | by Lea Starita
We generate data in our research labs to inform the classification of variants found in people like Chris and Jeanne Evert.
Read MoreJanuary 10, 2022 | by BBI Communications
Public health policy makers cannot move on unless and until a sustainable surveillance system is in place
Read MoreJanuary 07, 2022 | by BBI Communications
‘Conversations that Matter’ host Stuart McNish interviews BBI’s Dr. Brian Shirts who articulates the imperative of genetic testing and the services of connecting with family members through ConnectMyVariant.
Read MoreNovember 22, 2021 | by BBI Communications
A Flyer, Lecture, and Meeting on Mouse Brains Spawn 4-Year Study and Expected Future Research
Read MoreOctober 28, 2021 | by BBI Communications
Today we are joined by BBI member Dr. Heather Gustafson, Assistant Professor in the Ben Towne Center for Childhood Cancer Research at Seattle Children’s Hospital
Read MoreOctober 21, 2021 | by BBI Communications
This October marks the one-year anniversary of the Atlas of Variant Effects (AVE) Alliance.
Read MoreOctober 20, 2021 | by BBI Communications
UW Medicine’s Dr. Colin Pritchard, a leader in molecular diagnostics for cancer, has received the Catalyst for Precision Medicine Award from Scientific American.
Read MoreSeptember 21, 2021 | by BBI Communications
BBI’s Dr. Doug Fowler on September 16 presented at a National Human Genome Institute’s (NHRGI) “Bold Predictions”: The clinical relevance of all encountered genomic variants will be readily predictable, rendering the diagnostic designation “variant of uncertain significance (VUS)” obsolete.
Read MoreSeptember 09, 2021 | by Written by Michael McCarthy for UW Medicine Newsroom
The National Institutes of Health has awarded $16 million to UW Medicine scientists and their collaborators to fund two projects within the consortium. The funding is part of a 5-year, $185-million initiative sponsored by the NIH’s National Human Genome Research Institute.
Read MoreAugust 19, 2021 | by By Paige Cornwell, Seattle Times staff reporter
The Greater Seattle Coronavirus Assessment Network has sent out twice the usual number of its home-based test kits, which are used to track the spread of COVID-19 in the region, said Dr. Lea Starita
Read MoreAugust 18, 2021 | by Gailen Greenstein
This year BBI has three undergraduate interns working at the Fred Hutch, Seattle Children’s Hospital, and the UW Medicine: Amira Ellison, Heidi Solis, and Maria E. Benitez-Cortez. Here, each one offers insights into their passions for their work.
Read MoreJuly 28, 2021 | by BBI Communications
A new scientific study led by Brotman Baty Institute members offers insights into pregnant women with preeclampsia and the association between the severity of the condition and high-circulating cell-free DNA.
Read MoreJuly 17, 2021 | by Keith Eldridge, KOMO-TV News
This story briefly explains Dr. Shirts' hereditary cancer study, ConnectMyVariant
Read MoreJuly 16, 2021 | by BBI Communications
NIH Funds BBI members to participate in new Mendelian Genomics Research Consortium
Read MoreJuly 01, 2021 | by BBI Communications
New ‘sci-Space’ method, ‘like an intricately folded origami,’ allows measurement and visualization of growth from the moment of conception
Read MoreJuly 01, 2021 | by BBI Communications
BBI member Dr. Sarah Baxter MD, PhD, is Acting Assistant Professor in the Department of Pediatrics at UW, and Attending Physician in Pediatric Rheumatology at Seattle Children’s Hospital.
Read MoreJune 17, 2021 | by BBI Communications
BBI Administrative Director Nola Klemfuss and Research Coordinator Peter Han received the University’s “Together We Will” award for their outstanding contributions during “the extraordinary challenges of 2020.”
Read MoreJune 11, 2021 | by BBI Communications
Members of the Brotman Baty Institute for Precision Medicine (BBI) are using electronic health records to identify women with a risk of having a genetic predisposition to breast cancer.
Read MoreJune 01, 2021 | by BBI COMMUNICATIONS
“Although recent advances have led to a surge in the number of therapies available to treat Multiple Myeloma, it remains a challenge to identify which treatment a patient is most likely to respond to.” Dr. David Coffey, Fred Hutchinson Cancer Research Center
Read MoreJune 01, 2021 | by BBI Communications
BBI member Dr. Sarah Leary is an attending physician in the Cancer and Blood Disorders Center at Seattle Children’s Hospital and Associate Professor of Pediatrics at the University of Washington School of Medicine
Read MoreMay 28, 2021 | by BBI Communications
Old protocol ‘required instruments that cost as much as my condo and required pretty specialized training to run,’ research coordinator says.
Read MoreMay 26, 2021 | by BBI Communications
On May 19, The Brotman Baty Institute and Seattle Children’s co-hosted a one-day Pediatric Sequencing Symposium. Sessions ranged from the genomics of pediatric epilepsy disorders, to extended family outreach after finding hereditary cancer risk.
Read MoreMay 13, 2021 | by BBI Communications
NOTE: The Brotman Baty Institute for Precision Medicine (BBI), in fulfilling its goal to create a community of investigators across its three founding institutions, awards grants each year to advance basic science and translational research related to precision medicine.
Read MoreMay 11, 2021 | by Maggie Koerth, Sinduja Srinivasan and Anna Rothschild
BBI's Dr. Helen Chu provides insights on the effects of COVID-19 on children.
Read MoreMay 03, 2021 | by BBI COMMUNICATIONS
“There is a need for better tools to identify a precise genetic diagnosis in individuals when conventional testing approaches have been exhausted.” – Dr. Evan Eichler, Professor of Genome Sciences, UW School of Medicine
Read MoreApril 28, 2021 | by BBI Communications
The project, SeqFirst, will provide early access to whole-genome sequencing (WGS) to 100 children suspected of having developmental differences at the point of diagnosis.
Read MoreApril 19, 2021 | by BBI COMMUNICATIONS
BBI’s Scientific Director Dr. Jay Shendure and Principal Investigator Dr. Helen Chu briefed Washington Governor Jay Inslee on Friday (April 16th) on the institute’s work regarding the Seattle Flu Study, progress on studying COVID-19 transmission and variants, and other issues.
Read MoreApril 08, 2021 | by BBI Communications
BBI co-hosted with the Center for the Multiplex Assessment of Phenotype on April 5, 6, and 7 the fourth annual Mutational Scanning Symposium with global experts sharing their expertise. The Institute's Drs. Lea Starita and Doug Fowler share their observations.
Read MoreApril 01, 2021 | by BBI Communications
An international consortium of geneticists, biologists, clinicians, mathematicians, and other scientists is determined to take the study of the human genome to the next level – creating a comprehensive atlas of genetic variants to advance the understanding, diagnosis, and treatment of disease.
Read MoreApril 01, 2021 | by BBI Communications
BBI Faculty Conversations: A recurring profile of BBI members from our partner institutions: UW Medicine, The Fred Hutchison Cancer Research Center, and Seattle Children's.
Read MoreMarch 29, 2021 | by Fox 13 News - Salt Lake City
This story provides information on the risk of hereditary cancers and BBI's ConnectMyVariant project.
Read MoreMarch 11, 2021 | by CBS News
BBI's Dr. Helen Chu is the only researcher interviewed for this story on CBS News: This Morning
Read MoreMarch 01, 2021 | by BBI Communications
BBI Faculty Conversations. Check back in soon for more chats with BBI members from our partner institutions. Get an inside view of their work and where they think the field of precision medicine is heading.
Read MoreFebruary 21, 2021 | by BBI Communications
Students, teachers, and staff in Snohomish School District schools will be participating in a COVID-19 testing project with researchers at the University of Washington School of Medicine to gain new insights into the transmission of the virus in schools and classrooms.
Read MoreFebruary 10, 2021 | by BBI Communications
February 10 marked the first public release of data from the international Trans-Omics for Precision Medicine (TOPMed) program, one of the world’s largest genome sequencing projects ever conducted. BBI’s Debbie Nickerson and her researchers have and will continue to play a significant role.
Read MoreFebruary 01, 2021 | by BBI Communications
BBI member Tim Cherry is an Assistant Professor at the University of Washington School of Medicine in the Department of Pediatrics, Division of Genetic Medicine and a Principal Investigator at Seattle Children’s Research Institute in the Center for Developmental Biology and Regenerative Medicine
Read MoreJanuary 15, 2021 | by BBI Communications
Researchers in Seattle have mapped gene expression and DNA accessibility within individual cells across 15 fetal tissues. The findings are presented in back-to-back publications in the November 13, 2020 issue of the journal Science.
Read MoreJanuary 15, 2021 | by BBI Communications
Dr. Chu led the team that discovered first COVID-19 case of community spread in the United States.
Read MoreNovember 04, 2020 | by UW Medicine Newsroom
Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies. Such tests, which look for variants in the cell-free DNA that tumors shed into the blood plasma, help determine suitable treatment options.
Read MoreNovember 01, 2020 | by By James Glanz
The White House did not take basic steps to investigate its outbreak. We worked with geneticists to sequence the virus that infected two journalists exposed during the outbreak, providing clues to how it may have spread.
Read MoreSeptember 15, 2020 | by UW Medicine Newsroom
Researchers at UW Medicine in Seattle and Apple Inc. will launch a study to learn if physiological measurements from Apple Watch, like heart rate or blood oxygen, can be used to detect signs of acute respiratory infections, such as influenza and COVID-19, early.
Read MoreSeptember 14, 2020 | by BBI Communications
The Husky Coronavirus Testing program is powered by the Seattle Flu Study – the group that was the first to report community spread of COVID-19 in the United States.
Read MoreSeptember 01, 2020 | by BY ELEANOR LICATA | PHOTOS BY DENNIS WISE
February 2020 might seem a lifetime ago, but that’s when UW Medicine researchers were the first to report community spread of the novel coronavirus in the United States.
Read MoreJuly 23, 2020 | by Benjamin Cassidy, Seattle Met magazine
Collaboration, serendipity, and a whole lot of brainpower
Read MoreJuly 14, 2020 | by Brotman Baty Communications
At the end of 2019, Chinese health officials confirmed they were treating dozens of pneumonia cases with an unknown cause. It was a new coronavirus, SARS-CoV-2. UW Medicine researchers and clinicians prepared as cases began to spread across the globe.
Read MoreMay 05, 2020 | by BBI Communications
The number of COVID-19 infections in King County has been on the decline since the end of March, according to two recent reports from the Bellevue-based Institute for Disease Modeling (IDM) and the Greater Seattle Coronavirus Assessment Network (SCAN).
Read MoreMay 01, 2020 | by BBI Communications
This letter from several BBI members, published in The New England Journal of Medicine, articulates the Seattle Flu Study as an effective model surveillance system for tracking COVID-19
Read MoreApril 13, 2020 | by BBI Communications
The dynamics of gene expression across the genome can be characterized as a cell develops, and as it responds to challenges.
Read MoreMarch 23, 2020 | by BBI Communications
SCAN works in partnership with Public Health – Seattle & King County to help public health leaders respond to the coronavirus (COVID-19) outbreak.
Read MoreMarch 10, 2020 | by Heather Cheng, M.D., Ph.D.
Despite caveats in ads and on packages, users can fail to understand their limitations
Read MoreFebruary 26, 2020 | by Bill Conroy and Rob Smith
Shendure serves as a professor of genome sciences at the University of Washington and as the scientific program director at the Brotman Baty Institute for Precision Medicine
Read MoreFebruary 05, 2020 | by Bill Conroy, Seattle Business Magazine
Daring Women Q&A: Dr. Tina Lockwood heads a working group that is applying genetic tools to advance the detection and diagnosis of cancers and other diseases
Read MoreJanuary 29, 2020 | by Michelle Archer, Seattle Times Explore
Meet Lea Starita, a Seattle-based genome scientist who is working to understand how our individual genes impact our health. Here, she answers some questions about her work.
Read MoreJanuary 27, 2020 | by BBI Communications
Looking back at advances made by BBI members in 2019
Read MoreDecember 12, 2019 | by Brotman Baty Communications
Symposium will welcome international leaders to Seattle
Read MoreDecember 12, 2019 | by BBI Communications
Brotman Baty Institute for Precision Medicine (BBI) and Center for the Multiplex Assessment of Phenotype will co-sponsor a two-day Deep Mutational Scanning Symposium & Workshop in Seattle on Jan. 13 and 14, 2020.
Read MoreDecember 06, 2019 | by UW Medicine Communications
sci-Plex profiles gene expression in thousands of individual cells when a sample is perturbed; the technology holds promise for cancer, infection, prenatal medicine and other research.
Read MoreOctober 22, 2019 | by Brotman Baty Communications
The precision medicine institute welcomes the counsel of six leaders in business, philanthropy, and medicine.
Read MoreAugust 01, 2019 | by SABRINA RICHARDS, FRED HUTCH NEWS SERVICE
Tumors that turn off androgen receptor may have turned on new drug target
Read MoreJuly 26, 2019 | by UW Medicine Communications
Names that label certain cancer risk genes as sex- or organ-specific can dissuade people who need to be tested, according to Nature commentary.
Read MoreJune 26, 2019 | by Michael McCathy, MD
The Brotman Baty Institute for Precision Medicine (BBI) launched its cell-free DNA (cfDNA) working group in 2018, awarding grants for more than a dozen pilot studies to apply a cfDNA assay developed and validated by BBI to address a wide variety of clinical challenges.
Read MoreJune 10, 2019 | by By Michael McCarthy
Sequencing cell-free DNA found in blood plasma could provide patients with advanced disease an alternative to biopsy
Read MoreJune 10, 2019 | by Michael McCarthy
The study shows how genomic analysis can identify drugs that precisely target specific disease-causing mutations.
Read MoreFebruary 20, 2019 | by Allen Research Communications
A new study by researchers at the Allen Discovery Center at UW Medicine has traced that important period of organ formation, cell by cell, in the developing mouse.
Read MoreFebruary 18, 2019 | by Brotman Baty Communications
A manuscript published by BBI researchers Junyue Cao, Cole Trapnell and Jay Shendure profiled ~2 million cells, derived from 61 embryos staged between 9.5 and 13.5 days of gestation, in a single experiment.
Read MoreFebruary 11, 2019 | by Roy Smythe Insights Contributor, Forbes magazine
In the last 15 years, an explosion of patient data in the form of genetic information and electronic health records has sharpened the doctor’s picture of the individual patient—and of treatments tailored to their precise needs.
Read MoreNovember 08, 2018 | by Jay Shendure, Greg Findlay, Lea Starita
More than 1 million women have had genetic testing of BRCA1 and BRCA2, genes in which mutations can dramatically increase the risk for early onset breast and ovarian cancer. But for many women the test results have been ambiguous.
Read MoreNovember 05, 2018 | by Katherine Long, Seattle Times staff reporter
The NIH is asking for volunteers in a project to sequence the genetic material of a million people living in the U.S., making it possibly the largest research project in human history.
Read MoreOctober 18, 2018 | by Sabin Russell, Fred Hutch News Service
The effort to pick new vaccines to block ever-evolving flu viruses requires both science and serendipity.
Read MoreOctober 18, 2018 | by Lindsay Kurs, Seattle Childrens
Genetically engineered fish advance the study of how different genes affect development and cause disease.
Read MoreOctober 10, 2018 | by Clare McGrane, GeekWire
UW Associate Professor Su-In Lee has developed an AI system called Prescience that uses patient data to predict which patients are at risk of hypoxemia, or abnormally low blood oxygen.
Read MoreMay 17, 2018 | by UW Medicine Newsroom
An automated system that uses robots has been designed to rapidly produce human mini-organs derived from stem cells.
Read More