BBI Faculty Conversations: Dr. Fuki Hisama

August 15, 2022 | by BBI

BBI Member Dr. Fuki Hisama is a professor in the Department of Medical Genetics and medical director of the University of Washington Genetic Medicine Clinic.

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An Enlightening Exchange on Research and Public Health Issues Between Anthony Fauci and BBI’s Larry Corey

August 10, 2022 | by BBI Communications

President Biden’s Chief Medical Advisor Dr. Anthony Fauci joined BBI’s Dr. Larry Corey August 9 in an engaging conversation covering their work together on HIV-AIDS starting in the 1980s, as well as sharing insights on the coronavirus, monkeypox, and other significant public health issues.

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Researchers Gain Insights on Developmental Defects by Mapping Stages of Fruit Fly Embryo Growth

August 09, 2022 | by The European Molecular Biology Laboratory

Scientists have constructed the most complete and detailed single-cell map of embryo development in any animal to date, using the fruit fly as a model organism.

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BBI Interns Committed to Using Science to Improving People’s Lives as Future Researchers or Physicians – or Both

August 08, 2022 | by BBI Communications

One was the valedictorian of her high school class, in a Los Angeles County public school that did not have a college counselor. Another is a member of the Chickasaw Nation. And the third is fluent in Akan, the most widely spoken indigenous language in Ghana, West Africa.

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UW Medicine-BBI SCAN Program Sunsetting; Seattle Flu Study becomes Seattle Flu Alliance

July 28, 2022 | by BBI Communications

The Seattle Flu Study (SFS) and Greater Seattle Coronavirus Assessment Network Study (SCAN) are ending their active recruitment and research on July 31, 2022, after years of contributing to scientific discovery and improving public health in Seattle

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Associations between Ovarian Cancer Survival and Inflammatory Diet

July 25, 2022 | by BBI Communications

BBI Member Dr. Holly Harris Collaborates on Paper with Researchers at Several Other Institutions Identifying New Insights on Extending Survival Pre-and Post-Diagnosis

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Promising Young Scientist Anna-Lisa Doebley: A Penchant for Solving Puzzles Leads to A Passion for Identifying Cancer Subtypes

July 20, 2022 | by BBI Communications

What are three characteristics necessary to identify subtypes of cancer from cell-free DNA? The ability to solve difficult genetic computational problems, a high level of enthusiasm for translational cancer research, and a passion for improving the outcomes for cancer patients.

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The Future of Precision Medicine: Analogous to the Discovery of the X-Ray and Development of Radiology

June 30, 2022 | by BBI Communications

BBI’s Dr. Colin Pritchard believes that to chart the future of precision medicine, one needs to look no further than the development of radiology.

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BBI Faculty Conversations: Dr. Manu Setty

June 28, 2022 | by BBI

Today we are joined by BBI Member Dr. Manu Setty, assistant professor in the Herbold Computational Biology Program at Fred Hutchinson Cancer Center.

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Genome Sciences Hosting ‘DNA Café' featuring Ice Cream and Genomics

June 28, 2022 | by BBI Communications

Genomics and your favorite ice cream sundae: What could be better?

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Q&A: Highlights of the 2022 Mutational Scanning Symposium

June 27, 2022 | by BBI Communications

Organizer Dr. Fritz Roth and keynote speakers Drs. Clare Turnbull and Doug Fowler offer their observations and insights of the event and suggestions for the 2023 symposium to be held in the U.K.

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BBI’s Andrew Stergachis Named a Pew Biomedical Scholar to Study ‘Uncharted Regions of the Human Genome'

June 23, 2022 | by BBI Communications

Funding ‘provides resources and intellectual freedom to make a lasting impact on the future of epigenetics research’

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Promising Young Scientist Florence Chardon: ‘Determined and Focused’ on Overcoming Challenges in Genomics

June 21, 2022 | by BBI Communications

Florence Chardon’s introduction to scientific concepts started when she was old enough to understand dinnertime conversations with her parents and two older sisters. Her mother and father, both European physicists, would hold court usually on one of two topics: science or world politics.

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BBI Provides $50,000 Grant to Evaluate Performance of Novel Diagnostic Techniques

June 20, 2022 | by BBI Communications

Funding will enable mentoring of UW Medicine fellow and compare optical genome mapping with proximity ligation sequencing

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BBI’s Helen Chu to co-lead regional study on COVID-19 vaccine effectiveness

June 09, 2022 | by UW Medicine Communications

Researchers seeking to 3,500 children and adults to assess how well vaccines protect against COVID-19 infection

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Promising Young Scientists: Mohamed Adil:

June 01, 2022 | by BBI Communications

The Relentless Pursuit of Computational Genomics, Biomarkers, and Precision Medicine

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BBI Faculty Conversations: Dr. Jay Sarthy

May 27, 2022 | by BBI

BBI Member Dr. Jay Sarthy is an assistant professor of pediatrics in the Division of Hematology, Oncology and Bone Marrow Transplantation at the University of Washington School of Medicine.

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BBI's Evan Eichler Named to TIME Magazine's 100 Most Influential

May 25, 2022 | by Excerpted from UW Medicine press release

BBI’s Dr. Evan Eichler has been named to the 2022 TIME 100, the magazine’s annual list of the hundred most influential people over the past year.

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Q&A with Dr. Frederick Roth

May 17, 2022 | by BBI Communications

Lead organizer of the 5th Annual Mutational Scanning Symposium, in-person and online, June 13 and 14 in Toronto

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Promising Young Scientist Debora Ferede: Compassionate Commitment Toward Underserved Communities

May 16, 2022 | by BBI Communications

It’s become a cliché: “They are wise beyond their years.” Unless you’re referring to Debora Ferede.

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Gene that shapes mutation rate variation found in mice

May 12, 2022 | by Michael McCarthy

The finding supports theory that genetic differences between individuals and species can affect the acquisition of mutations.

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The Backstory of the First Complete Sequence of the Human Genome

April 29, 2022 | by BBI Communications

A Q&A with BBI researchers reveals why the merger of two sequencing systems was crucial to landmark study

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BBI’s Danny Miller Leading New Effort Offering Sequencing Services

April 29, 2022 | by BBI Communications

BBI’s Dr. Danny Miller and the UW’s Nanopore Sequencing Core are providing both targeted and whole genome long read sequencing on the Oxford Nanopore platform to assist other researchers with their projects.

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5th Annual Mutational Scanning Symposium Set for June in Toronto

April 28, 2022 | by BBI Communications

With just six weeks away from the opening session, the fifth annual Mutational Scanning Symposium, to be held in-person and online June 13 and 14 in Toronto, now has most of its speakers confirmed.

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BBI Faculty Conversations: Dr. Alison Paquette

April 28, 2022 | by BBI

BBI Member Alison Paquette, PhD, is an Assistant Professor in the Department of Pediatrics at the University of Washington School of Medicine and a member of the Seattle Children's Research Institute's Center for Developmental Biology and Regenerative Medicine.

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BBI Funds Immunotherapy Research to Help Address Pancreatic and Kidney Cancers, a Project that ‘Exemplifies Precision Medicine’

April 12, 2022 | by BBI Communications

‘Killing is not the hard part for the immune system. The hard part is precisely killing the right thing.’

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BBI's Dr. Trevor Bedford: COVID-19 'Likely to Keep Evolving'

April 07, 2022 | by BBI Communications

'The evolution has been remarkably fast so far'

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BBI's Dr. Evan Eichler a Lead Author on Paper of First Complete Human Genome Map

April 01, 2022 | by BBI Communications

‘Our view of how humans differ from each other is going to be transformed’

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Promising Young Scientists - Amanda Riley: Raising Questions - and Identifying Answers - on the Complexities of Lung Cancer

April 01, 2022 | by BBI Communications

Take one enthusiastic high school science teacher. Combine with summer internships at an international pharmaceutical company and a leading academic research center. The result is an inspired college undergraduate and promising young scientist. That was Amanda Riley seven years ago.

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Mentors Helped Launch His Award-winning Career. Now, It’s His Turn.

March 31, 2022 | by Stephanie Perry, UW Medicine Communications Specialist

Alumnus Dr. Colin Pritchard’s genetic research career and his gift to help future researchers.

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BBI Hosting Monthly Viruses and Vaccines Seminar Series

March 30, 2022 | by BBI Communications

BBI is sponsoring a “Viruses and Vaccines Seminar Series.”

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Fifth Annual Mutational Scanning Symposium Planned for Toronto in June

March 29, 2022 | by BBI Communications

The Brotman Baty Institute is co-sponsoring the fifth annual Mutational Scanning Symposium to be held in-person and online June 13 and 14 in Toronto, followed by an online only poster session on June 16th. More information, including registration details, are available here.

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We Study Virus Evolution. Here’s Where We Think the Coronavirus Is Going.

March 28, 2022 | by Sarah Cobey, Jesse Bloom and Tyler Starr, and Nathaniel Lash

NOTE: BBI’s Dr. Jesse Bloom and his lab colleague Dr. Tyler Starr are two of the four co-authors on this op-ed published March 28 in The New York Times. To observe the compelling accompanying graphics, please click here.

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Initial SeqFirst Results are Promising for Genome Sequencing on Infants

March 28, 2022 | by BBI Communications

Initial results of the BBI-sponsored SeqFirst Project using whole genome sequencing have demonstrated that “clear opportunities exist to center equity for providing a precise genetic diagnosis that adds value to the care of critically ill newborns.”

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UW Regents Approve New Building for BBI Labs and Offices

March 25, 2022 | by BBI Communications

BBI will be part of a major development approved recently by the UW Board of Regents – an 11-story building in the Portage Bay Crossing area on the west side the UW campus.

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NIH All of Us Research Program releases genomic dataset

March 17, 2022 | by UW Medicine

The nearly 100,000 whole genome sequences reflect contributions from diverse participants.

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‘Roadmap’ tracks trajectories of embryo development

March 14, 2022 | by UW Medicine | Newsroom

BBI scientists and others have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.

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BBI Funds ‘Entirely Novel Approach’ to Studying Pediatric Leukemia

February 28, 2022 | by BBI Communications

‘Hope to potentially deliver more information and more confidence in assessing the potential – or even likelihood – of children relapsing’

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BBI Faculty Conversations - Dr. Swati Shree

February 28, 2022 | by BBI Communications

Today we are joined by BBI member Dr. Swati Shree, Assistant Professor in Maternal Fetal Medicine in the Department of Obstetrics and Gynecology at the University of Washington.

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BAT Lab joining UW Initiative to Combat Wildlife Trafficking

February 17, 2022 | by BBI Communications

The Brotman Baty Institute Advanced Technology Lab (BAT Lab) will soon be evaluating animal and plant specimens as part of a new UW initiative to help combat international wildlife trafficking.

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‘Closing the Gap’ Paper Examines BBI’s Progress Toward Resolving Genetic Variants of Unknown Significance

February 14, 2022 | by BBI Communications

“Technological advances are making the routine sequencing of human genomes increasingly practical, including in clinical settings. However, our inability to interpret the clinical consequences of genetic variants discovered by sequencing remains a critical roadblock.”

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KUOW interview with Dr. Helen Chu

February 07, 2022 | by BBI Communications

Dr. Helen Chu discusses Covid testing with Kim Malcolm

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Vancouver Sun profile of Ashley Doyle

February 02, 2022 | by BBI Communications

Ashley Doyle, a client of BBI’s ConnectMyVariant with hereditary cancer, is making a ‘Herculean effort” to connect with relatives near and far, urging them to seek genetic testing.

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Promising Young Scientists: Moez Dawood

January 28, 2022 | by BBI Communications

Moez Dawood: Pushing Himself Outside His Comfort Zone and Using BBI Technologies to Address Unanswered Questions in Human Genetics

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Are We Prepared for the Next Pandemic?

January 24, 2022 | by BBI Communications

Storylines: Bloomberg Businessweek documentary examines Seattle Flu Study with BBI’s Drs. Lea Starita and Trevor Bedford

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‘Continuum of Expertise’ of International Researchers Examines Pediatric Epilepsy

January 24, 2022 | by BBI Communications

‘It’s one thing to find a genetic variant. But how does that affect the brain architecture, structure, and function? We wanted to know more.’

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Chris Evert and the Imperative of Studying Genetic Variants

January 19, 2022 | by Lea Starita

We generate data in our research labs to inform the classification of variants found in people like Chris and Jeanne Evert.

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New Commentary Offers Reforms to Regulations That Hindered Seattle Flu Study Surveillance of SARS-CoV-2

January 10, 2022 | by BBI Communications

Public health policy makers cannot move on unless and until a sustainable surveillance system is in place

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Dr. Brian Shirts interviewed for 'Conversations That Matter'

January 07, 2022 | by BBI Communications

‘Conversations that Matter’ host Stuart McNish interviews BBI’s Dr. Brian Shirts who articulates the imperative of genetic testing and the services of connecting with family members through ConnectMyVariant.

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International Collaboration Leads to New Insights on Fetal Brain Development

November 22, 2021 | by BBI Communications

A Flyer, Lecture, and Meeting on Mouse Brains Spawn 4-Year Study and Expected Future Research

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BBI Faculty Conversations: Dr. Heather Gustafson

October 28, 2021 | by BBI Communications

Today we are joined by BBI member Dr. Heather Gustafson, Assistant Professor in the Ben Towne Center for Childhood Cancer Research at Seattle Children’s Hospital

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Looking Back and Projecting Ahead as AVE Celebrates One Year

October 21, 2021 | by BBI Communications

This October marks the one-year anniversary of the Atlas of Variant Effects (AVE) Alliance.

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Scientific American Honors UW Cancer Researcher Colin Pritchard

October 20, 2021 | by BBI Communications

UW Medicine’s Dr. Colin Pritchard, a leader in molecular diagnostics for cancer, has received the Catalyst for Precision Medicine Award from Scientific American.

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BBI’s Dr. Doug Fowler: Q&A on NHGRI’s Bold Predictions for Human Genomics by 2030

September 21, 2021 | by BBI Communications

BBI’s Dr. Doug Fowler on September 16 presented at a National Human Genome Institute’s (NHRGI) “Bold Predictions”: The clinical relevance of all encountered genomic variants will be readily predictable, rendering the diagnostic designation “variant of uncertain significance (VUS)” obsolete.

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NIH Awards BBI Researchers $16 million as Part of ‘Impact of Genome Variation on Function’ Consortium

September 09, 2021 | by Written by Michael McCarthy for UW Medicine Newsroom

The National Institutes of Health has awarded $16 million to UW Medicine scientists and their collaborators to fund two projects within the consortium. The funding is part of a 5-year, $185-million initiative sponsored by the NIH’s National Human Genome Research Institute.

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Demand for coronavirus tests soars in Seattle amid increased travel, concerns about delta variant

August 19, 2021 | by By Paige Cornwell, Seattle Times staff reporter

The Greater Seattle Coronavirus Assessment Network has sent out twice the usual number of its home-based test kits, which are used to track the spread of COVID-19 in the region, said Dr. Lea Starita

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Interns Advance BBI’s Work as They ‘Deepen Knowledge and Experience’

August 18, 2021 | by Gailen Greenstein

This year BBI has three undergraduate interns working at the Fred Hutch, Seattle Children’s Hospital, and the UW Medicine: Amira Ellison, Heidi Solis, and Maria E. Benitez-Cortez. Here, each one offers insights into their passions for their work.

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New UW Medicine-BBI Study Identifies Association Between Severity of Preeclampsia and Cell-Free DNA

July 28, 2021 | by BBI Communications

A new scientific study led by Brotman Baty Institute members offers insights into pregnant women with preeclampsia and the association between the severity of the condition and high-circulating cell-free DNA.

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Hereditary Cancer Project at UW Medicine Brotman Baty Institute for Precision Medicine

July 17, 2021 | by Keith Eldridge, KOMO-TV News

This story briefly explains Dr. Shirts' hereditary cancer study, ConnectMyVariant

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Exploring Underlying Causes of Mendelian Conditions Difficult to Solve

July 16, 2021 | by BBI Communications

NIH Funds BBI members to participate in new Mendelian Genomics Research Consortium

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‘Leading-Edge’ Technology Enables Scientists to Map Mouse Development

July 01, 2021 | by BBI Communications

New ‘sci-Space’ method, ‘like an intricately folded origami,’ allows measurement and visualization of growth from the moment of conception

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BBI Faculty Conversations – Dr. Sarah Baxter

July 01, 2021 | by BBI Communications

BBI member Dr. Sarah Baxter MD, PhD, is Acting Assistant Professor in the Department of Pediatrics at UW, and Attending Physician in Pediatric Rheumatology at Seattle Children’s Hospital.

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Two BBI Staff Receive UW ‘Together We Will’ Honors

June 17, 2021 | by BBI Communications

BBI Administrative Director Nola Klemfuss and Research Coordinator Peter Han received the University’s “Together We Will” award for their outstanding contributions during “the extraordinary challenges of 2020.”

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Study of Electronic Health Records Demonstrates Value of Data in Referring Patients for Genetic Testing

June 11, 2021 | by BBI Communications

Members of the Brotman Baty Institute for Precision Medicine (BBI) are using electronic health records to identify women with a risk of having a genetic predisposition to breast cancer.

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BBI ‘Catalytic Collaboration’ Grant Leads to ‘Extraordinary’ Progress in Research for Directing Treatment of Multiple Myeloma Patients

June 01, 2021 | by BBI COMMUNICATIONS

“Although recent advances have led to a surge in the number of therapies available to treat Multiple Myeloma, it remains a challenge to identify which treatment a patient is most likely to respond to.” Dr. David Coffey, Fred Hutchinson Cancer Research Center

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BBI Faculty Conversations: Dr. Sarah Leary

June 01, 2021 | by BBI Communications

BBI member Dr. Sarah Leary is an attending physician in the Cancer and Blood Disorders Center at Seattle Children’s Hospital and Associate Professor of Pediatrics at the University of Washington School of Medicine

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Student-led project improves COVID-19 testing efficiency

May 28, 2021 | by BBI Communications

Old protocol ‘required instruments that cost as much as my condo and required pretty specialized training to run,’ research coordinator says.

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Pediatric Sequencing Symposium: A Q&A with Dr. Ghayda Mirzaa, Dr. Tim Cherry, and Dr. Samuel Huang

May 26, 2021 | by BBI Communications

On May 19, The Brotman Baty Institute and Seattle Children’s co-hosted a one-day Pediatric Sequencing Symposium. Sessions ranged from the genomics of pediatric epilepsy disorders, to extended family outreach after finding hereditary cancer risk.

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BBI ‘Catalytic Collaboration Grant’ funded in 2019 Leads to Promising Genetic Diagnoses of Rare Diseases

May 03, 2021 | by BBI COMMUNICATIONS

“There is a need for better tools to identify a precise genetic diagnosis in individuals when conventional testing approaches have been exhausted.” – Dr. Evan Eichler, Professor of Genome Sciences, UW School of Medicine

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Brotman Baty Institute Collaborates with Illumina and GeneDx on Whole-Genome Sequencing Study to Support Families of Children with Developmental Differences

April 28, 2021 | by BBI Communications

The project, SeqFirst, will provide early access to whole-genome sequencing (WGS) to 100 children suspected of having developmental differences at the point of diagnosis.

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BBI’s Jay Shendure and Helen Chu Brief Washington Governor Jay Inslee on Progress on COVID-19

April 19, 2021 | by BBI COMMUNICATIONS

BBI’s Scientific Director Dr. Jay Shendure and Principal Investigator Dr. Helen Chu briefed Washington Governor Jay Inslee on Friday (April 16th) on the institute’s work regarding the Seattle Flu Study, progress on studying COVID-19 transmission and variants, and other issues.

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Lasting Impressions: BBI’s Lea Starita and Doug Fowler Reflect on the 2021 Mutational Scanning Symposium

April 08, 2021 | by BBI Communications

BBI co-hosted with the Center for the Multiplex Assessment of Phenotype on April 5, 6, and 7 the fourth annual Mutational Scanning Symposium with global experts sharing their expertise. The Institute's Drs. Lea Starita and Doug Fowler share their observations.

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Scientists Launch ‘Herculean’ Project Creating Atlas of Human Genome Variants

April 01, 2021 | by BBI Communications

An international consortium of geneticists, biologists, clinicians, mathematicians, and other scientists is determined to take the study of the human genome to the next level – creating a comprehensive atlas of genetic variants to advance the understanding, diagnosis, and treatment of disease.

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BYU researches hereditary cancer

March 29, 2021 | by Fox 13 News - Salt Lake City

This story provides information on the risk of hereditary cancers and BBI's ConnectMyVariant project.

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Coronavirus pandemic, one year later: A look back at key players, events during the crisis

March 11, 2021 | by CBS News

BBI's Dr. Helen Chu is the only researcher interviewed for this story on CBS News: This Morning

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Researchers Map Human Cell Atlases During Development

January 15, 2021 | by BBI Communications

Researchers in Seattle have mapped gene expression and DNA accessibility within individual cells across 15 fetal tissues. The findings are presented in back-to-back publications in the November 13, 2020 issue of the journal Science.

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Blood cell mutations confound prostate cancer liquid biopsy

November 04, 2020 | by UW Medicine Newsroom

Unrelated mutations, when present in the blood, can lead to false positive results in men with advanced prostate cancer who are undergoing liquid biopsies. Such tests, which look for variants in the cell-free DNA that tumors shed into the blood plasma, help determine suitable treatment options.

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Tests Show Genetic Signature of Virus That May Have Infected President Trump

November 01, 2020 | by By James Glanz

The White House did not take basic steps to investigate its outbreak. We worked with geneticists to sequence the virus that infected two journalists exposed during the outbreak, providing clues to how it may have spread.

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UW announces COVID-19 testing program for students, faculty and staff across all three campuses

September 14, 2020 | by BBI Communications

The Husky Coronavirus Testing program is powered by the Seattle Flu Study – the group that was the first to report community spread of COVID-19 in the United States.

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SCAN DATA UPDATE: Latest Reports Show COVID-19 Declining; Infections Found Across King County, Most Still Susceptible

May 05, 2020 | by BBI Communications

The number of COVID-19 infections in King County has been on the decline since the end of March, according to two recent reports from the Bellevue-based Institute for Disease Modeling (IDM) and the Greater Seattle Coronavirus Assessment Network (SCAN).

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The Problem with Direct-to-Consumer Genetic Tests

March 10, 2020 | by Heather Cheng, M.D., Ph.D.

Despite caveats in ads and on packages, users can fail to understand their limitations

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Dr. Jay Shendure: The 2020 Leaders in Health Care Gold Award Winner for Achievement in Medical Research

February 26, 2020 | by Bill Conroy and Rob Smith

Shendure serves as a professor of genome sciences at the University of Washington and as the scientific program director at the Brotman Baty Institute for Precision Medicine

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UW Professor Tina Lockwood Is Working to Improve Health Care for All Via DNA Research

February 05, 2020 | by Bill Conroy, Seattle Business Magazine

Daring Women Q&A: Dr. Tina Lockwood heads a working group that is applying genetic tools to advance the detection and diagnosis of cancers and other diseases

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BBI Scientific Impact in 2019

January 27, 2020 | by BBI Communications

Looking back at advances made by BBI members in 2019

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Deep Mutational Scanning Symposium & Workshop, Jan. 13 – 14

December 12, 2019 | by Brotman Baty Communications

Symposium will welcome international leaders to Seattle

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Technique shows how individual cancer cells react to drugs

December 06, 2019 | by UW Medicine Communications

sci-Plex profiles gene expression in thousands of individual cells when a sample is perturbed; the technology holds promise for cancer, infection, prenatal medicine and other research.

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Brotman Baty Institute Announces Formation of Advisory Board

October 22, 2019 | by Brotman Baty Communications

The precision medicine institute welcomes the counsel of six leaders in business, philanthropy, and medicine.

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New study reveals weakness in emerging type of aggressive prostate tumor

August 01, 2019 | by SABRINA RICHARDS, FRED HUTCH NEWS SERVICE

Tumors that turn off androgen receptor may have turned on new drug target

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Simpler name for cancer genetic syndrome could save lives

July 26, 2019 | by UW Medicine Communications

Names that label certain cancer risk genes as sex- or organ-specific can dissuade people who need to be tested, according to Nature commentary.

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BBI Cell-free DNA Working Group Assesses First Year of Progress

June 26, 2019 | by Michael McCathy, MD

The Brotman Baty Institute for Precision Medicine (BBI) launched its cell-free DNA (cfDNA) working group in 2018, awarding grants for more than a dozen pilot studies to apply a cfDNA assay developed and validated by BBI to address a wide variety of clinical challenges.

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Test reliably detects tumor mutations in blood of patients with advanced prostate cancer

June 10, 2019 | by By Michael McCarthy

Sequencing cell-free DNA found in blood plasma could provide patients with advanced disease an alternative to biopsy

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Drugs could treat some aneurysms, gene study suggests

June 10, 2019 | by Michael McCarthy

The study shows how genomic analysis can identify drugs that precisely target specific disease-causing mutations.

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2 million-cell experiment traces how a mammal grows, cell by single cell

February 20, 2019 | by Allen Research Communications

A new study by researchers at the Allen Discovery Center at UW Medicine has traced that important period of organ formation, cell by cell, in the developing mouse.

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Mouse Organogenesis Cell Atlas (MOCA)

February 18, 2019 | by Brotman Baty Communications

A manuscript published by BBI researchers Junyue Cao, Cole Trapnell and Jay Shendure profiled ~2 million cells, derived from 61 embryos staged between 9.5 and 13.5 days of gestation, in a single experiment.

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How Machine Learning Is Crafting Precision Medicine

February 11, 2019 | by Roy Smythe Insights Contributor, Forbes magazine

In the last 15 years, an explosion of patient data in the form of genetic information and electronic health records has sharpened the doctor’s picture of the individual patient—and of treatments tailored to their precise needs.

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BRCA mutations can be deadly or harmless. Now CRISPR can tell the difference

November 08, 2018 | by Jay Shendure, Greg Findlay, Lea Starita

More than 1 million women have had genetic testing of BRCA1 and BRCA2, genes in which mutations can dramatically increase the risk for early onset breast and ovarian cancer. But for many women the test results have been ambiguous.

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NIH visits UW to explain why they want your genome

November 05, 2018 | by Katherine Long, Seattle Times staff reporter

The NIH is asking for volunteers in a project to sequence the genetic material of a million people living in the U.S., making it possibly the largest research project in human history.

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Forecasting the shape of flu viruses to come

October 18, 2018 | by Sabin Russell, Fred Hutch News Service

The effort to pick new vaccines to block ever-evolving flu viruses requires both science and serendipity.

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Tailor-Made Fish Help Explain Genetic Conditions in Children

October 18, 2018 | by Lindsay Kurs, Seattle Childrens

Genetically engineered fish advance the study of how different genes affect development and cause disease.

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Univ. of Washington researchers unveil Prescience, an AI system that predicts problems during surgery

October 10, 2018 | by Clare McGrane, GeekWire

UW Associate Professor Su-In Lee has developed an AI system called Prescience that uses patient data to predict which patients are at risk of hypoxemia, or abnormally low blood oxygen.

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